Florida State Road 59

State Road 59 runs north to south through the eastern Florida Panhandle, with a northern terminus at U.S. [Route 90 (Florida)|US 90] near Lloyd, one major intersection at Interstate 10 at exit 217, and a southern terminus at U.S. [Route 98 (Florida)|US 98] in rural Jefferson County.
The route is extended at both ends by county roads; to the north through Leon County to the Georgia state line, where it becomes State [Route 122 (Georgia)|State Route 122] to Thomasville; and on the south via County Road 59, a former secondary state route, into the Saint Marks [National Wildlife Refuge].