Florida State Road 53
State Road 53 is a north–south state highway in the panhandle of northern Florida. Its southern terminus is an interchange with Interstate 10 near Lee and Madison; the northern terminus is at the Georgia state line near Cherry Lake, Florida. Part of SR 53, from Harvey Greene Drive north to SR 14, is also signed Florida [State Road 14 Truck|SR 14 Truck], a rare special state highway in Florida.
SR 53 continues northward from the state line as Georgia [State Route 333|State Route 333]. A southbound continuation of SR 53 is County Road 53, which ultimately ends at an intersection with U.S. [Route 27 in Florida|U.S. Route 27] in Buckville. This is also the western terminus of County Road [534 (Lafayette County, Florida)|CR 534].