Florida State Road 22

State Road 22 runs east and west from U.S. [Route 98 Business (Panama City, Florida)|US 98 Business] in Springfield to Florida State [Road 71|SR 71] in Wewahitchka. SR 22 is known as East 3rd Street in Springfield and Wewa Highway from Callaway to Wewahitchka. With the exception of the intersection with U.S. [Route 98 (Florida)|US 98] in Callaway, SR 22 is entirely a two-lane undivided highway, and is far more rural east of Callaway.
Beginning one block south of SR 22's eastern terminus, County Road 22 extends the route to the banks of the Apalachicola River. Several other disconnected segments of CR 22 exist in the Apalachicola National Forest and to the east in Liberty and Wakulla Counties, evidencing a former plan to extend SR 22 to Sopchoppy via Sumatra.