Extracting Cell Stiffness from Real-Time Deformability Cytometry: Theory and Experiment
Extracting Cell Stiffness from Real-Time Deformability Cytometry: Theory and Experiment is a scholarly work by Jochen Guck, Alexander Mietke, Oliver Otto, Philipp Rosendahl, Anna Taubenberger, Stefan Golfier, Elisabeth Fischer-Friedrich, and Salvatore Girardo, published in 2015 in ''Biophysical Journal''. The main subjects of the publication include cell mechanics, biological system, cytometry, materials science, biophysics, flow cytometry, hemorheology, mechanics, microfluidics, chemistry, stiffness, and biomedical engineering. Performing real-time deformability cytometry experiments on both model spheres of known elasticity and biological cells, authors demonstrate that the authors' analytical model not only predicts deformed shapes inside the channel but also allows for quantification of cell mechanical parameters.