Evolutionary constraints and the neutral theory
Evolutionary constraints and the neutral theory is a scholarly work, published in 1984 in ''Journal of Molecular Evolution''. The main subjects of the publication include evolutionary biology, neutral theory of molecular evolution, substitution, mutation rate, selection (genetic algorithm), mutation, neutral mutation, population genetics, rate of evolution, purifying selection, ribosome, gene, deoxyribonucleic acid, pseudogene, evolutionary dynamics, evolutionary constraint, genetics, molecular evolution, biology, point mutation, and natural selection. Rates slower than this indicate the presence of constraints imposed by negative (natural) selection, which rejects and discards deleterious mutations.