Evocative/suppression testing


Evocative/suppression testing refers to a class of tests performed where one substance is measured both before and after the administration of another substance to determine if the levels are stimulated or suppressed.
They are most commonly performed in the evaluation of possible endocrine disorders.
Certain tests are performed in the evaluation of multiple conditions, and not all listed substances may be measured in each test.
Examples include:
Test nameSubstance administeredSubstance measuredCondition evaluated
combined rapid anterior pituitary evaluation panelinsulin, GnRH, TRHACTH and cortisol, FSH, HGH, LH, prolactin, TSHhypopituitarism
TRH stimulation testTRHTSHsecondary hypothyroidism
ACTH stimulation testACTHcortisol, 17α-hydroxyprogesteroneadrenal insufficiency, Congenital adrenal hyperplasia
metyrapone panelmetyraponecortisol, 11-deoxycortisoladrenal insufficiency
dexamethasone suppression testdexamethasonecortisolCushing's syndrome
captopril suppression testcaptoprilaldosteroneprimary aldosteronism
captopril challenge testcaptoprilreninrenal artery stenosis