Ethinylestradiol/megestrol acetate

Ethinylestradiol/megestrol acetate, sold under the brand name Volidan among others, was a combination of ethinylestradiol, an estrogen, and megestrol acetate, a progestin, which was used as a birth control pill to prevent pregnancy in women. It was taken by mouth and contained 50 to 100 μg EE and 1 to 5 mg MGA per tablet. MGA-containing birth control pills were withdrawn after reports in the early 1970s of a high incidence of venous thromboembolism in association with the preparations.