Esco (name)
Esco may refer to the following people:
;Given name
- Esco Sarkkinen, American football player and coach
- Esco Haynes, American professional baseball player
- Esco Niblo Bowen, American lawyer, judge and politician
- Sigmund Esco Jackson, American singer and musician
- William Esco Moerner, American physical chemist and chemical physicist awarded Nobel Prize in Chemistry in 2014
;Nickname