Erythroparvovirus


Erythroparvovirus is a genus of viruses in subfamily Parvovirinae of the virus family Parvoviridae. There are seven species in this genus. Diseases associated with this genus include fifth disease and skin lesions.

Taxonomy

The genus contains the following species, listed by scientific name and followed by the exemplar virus of the species:Erythroparvovirus pinniped1, Seal parvovirusErythroparvovirus primate1, Human parvovirus B19Erythroparvovirus primate2, Simian parvovirusErythroparvovirus primate3, Rhesus macaque parvovirusErythroparvovirus primate4, Pig-tailed macaque parvovirusErythroparvovirus rodent1, Chipmunk parvovirusErythroparvovirus ungulate1, Bovine parvovirus 3

Structure

Viruses in Erythroparvovirus are non-enveloped, with icosahedral and round geometries, and T=1 symmetry. The diameter is around 18-26 nm. Genomes are linear, around 6kb in length.
GenusStructureSymmetryCapsidGenomic arrangementGenomic segmentation
ErythroparvovirusIcosahedralT=1Non-envelopedLinear-

Life cycle

Viral replication is nuclear. Entry into the host cell is achieved by attachment to host receptors, which mediates clathrin-mediated endocytosis. Replication follows the rolling-hairpin model. DNA-templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear pore export. Transmission routes are oral and respiratory.
GenusHost detailsTissue tropismEntry detailsRelease detailsReplication siteAssembly siteTransmission
ErythroparvovirusVertebratesoften restricted to erythroid progenitorsClathrin-mediated endocytosisCell lysisNucleusNucleusAerosol