Erythromycin/isotretinoin


Erythromycin/isotretinoin is a topical gel with two active ingredients: erythromycin 2% w/w and isotretinoin 0.05% w/w with a primary indication for the treatment of moderate acne vulgaris.
Isotretinoin is a pharmaceutical derivative of retinoic acid. Its mechanism of action is believed to involve reduction in the amount of sebum produced by sebaceous glands on the skin's surface.
Erythromycin is a bacteriostatic macrolide antibiotic used to treat bacterial infections, including the inhibition of bacteria linked with acne, such Cutibacterium acnes. The mechanism of action is poorly understood.

Side effects

Erythromycin/isotretinoin may cause a number of side effects, ranging from very common to rare. Most side effects affect the skin and have only a local effect to the place of application. Some of the side effects are related to vitamin A toxicity.
Very common Common Unknown frequency
Skin painDermatitisAllergic reaction
RashFacial swelling
Xeroderma Hives
Prunitis Abdominal pain
Skin burning sensationDiarrhea
Erythematous Skin photosensitivity
Skin irritationSkin discoloration
Skin peeling or scaling