EME
- College of Electrical and Mechanical Engineering
- Corps of Royal Canadian Electrical and Mechanical Engineers
- Disk encryption theory
- EME (psychedelic)
- EME Temple
- Early Medieval Europe (journal)
- Early Modern English
- Early myoclonic encephalopathy
- Earth–Moon–Earth communication
- Edison Mission Energy
- Eigenmode expansion
- Electromagnetic environment
- Electromembrane extraction
- Elmore railway station
- Emcor
- Encrypted Media Extensions
- English language
- Exempted Micro Enterprises
- Indian Army Corps of EME
- Pakistan Army Corps of Electrical and Mechanical Engineering