Irene
- 14 Irene
- 1981 Atlantic hurricane season
- 44 Scotland Street
- Assassination Classroom
- Bajazet (opera)
- Bloom (Beach House album)
- Destiny (Irene Adler)
- Drive (2011 film)
- Eirene (disambiguation)
- Eirini metro station
- Good Girls (comics)
- HMS Princess Irene
- Harry and the Hendersons
- Hurricane Irene
- Hurricane Irene (1999)
- Hurricane Irene (2005)
- Hurricane Irene–Olivia
- IRENE (technology)
- Iren (disambiguation)
- Irena (disambiguation)
- Irene (1926 film)
- Irene (1940 film)
- Irene (2002 film)
- Irene (2009 film)
- Irene (costume designer)
- Irene (given name)
- Irene (ketch)
- Irene (musical)
- Irene (play)
- Irene (singer)
- Irene (sternwheeler)
- Irene Adler
- Irene Iddesleigh
- Irene Lake
- Irene River (New Zealand)
- Irene River (Opawica River tributary)
- Irene incident
- Irene of Athens
- Irene, Gauteng
- Irene, South Dakota
- Irene, Texas
- Irene, West Virginia
- Irene-class cruiser
- Irina (disambiguation)
- Irina Jelavić
- Irène (tragedy)
- Lake Irene
- List of Fairy Tail characters
- List of SoltyRei characters
- Man on the Rocks
- Mitch Rapp
- Momentum (TobyMac album)
- Nella Larsen
- Operation Irini
- Rocky Mountain National Park
- TSS Irene (1885)
- Tamerlano
- The Forsyte Saga
- The Princess and the Goblin
- The Sleeper (poem)
- Tropical Storm Irene (1947)
- Tropical Storm Irene (1959)
- Warehouse 13