Effect of Extent of Supersaturation on the Evolution of Kinetic Solubility Profiles
Effect of Extent of Supersaturation on the Evolution of Kinetic Solubility Profiles is a scholarly work by Ping I Lee, published in 2016 in ''Molecular Pharmaceutics''. The main subjects of the publication include solubility equilibrium, bioavailability, chemistry, chemical engineering, drug delivery, thermodynamics, protein aggregation, precipitation, Dissolution, solubility, nucleation, supersaturation, chromatography, and crystallization. Solubility limited compounds require enabling formulations such as amorphous solid dispersions (ASDs) to increase the apparent solubility by dissolving to a concentration higher than the equilibrium solubility of the drug.