Edward Ayscough
Edward Ayscough may refer to:
- Edward Ayscu, or Ayscough, English historian
- Edward Ayscough (of Nuthall), MP for Stamford 1624
- Sir Edward Ayscough (born 1596), English MP for Lincoln and Lincolnshire
- Sir Edward Ayscough (died 1668), English MP for Great Grimsby 1659
- Sir Edward Ayscough (died 1699), English MP for Great Grimsby 1685–1699