Edward Holmes
Edward Holmes may refer to:
- Edward Holmes (architect), English architect
- Edward Holmes (field hockey), Irish field hockey player and Olympic medallist
- Edward Holmes (musicologist), English musicologist and music critic
- Edward Holmes (rugby), English rugby union player and referee
- Edward Lorenzo Holmes, American ophthalmologist
- Edward C. Holmes, British evolutionary biologist and virologist
- Edward Carleton Holmes, one of the solicitors who drew up the first rules of Rugby Football Union
- Edward Morell Holmes, British botanist, curator and lecturer
- Lefty Holmes, American baseball pitcher