ESI
- ESI Hospital metro station
- ESI Hospital metro station (Hyderabad)
- ESI register
- Earth Similarity Index
- Edge Side Includes
- Electro Scientific Industries
- Electromagnetic source imaging
- Electronically stored information (Federal Rules of Civil Procedure)
- Electrospray ionization
- Emergency Severity Index
- Employees' State Insurance
- Enhanced Station Initiative
- Enlightened self-interest
- Enterprise Southbridge Interface
- Environmental Seismic Intensity scale
- Environmental Sustainability Index
- Epidural steroid injection
- Ernst Strüngmann Institute
- Erwin Schrödinger International Institute for Mathematical Physics
- Escadron spécial d'intervention
- Esi Awuah
- Esi Benyarku
- Esi Buobasa
- Esi Edugyan
- Esi Lufo
- Esi Sutherland-Addy
- Esikeli Tonga
- Essential Science Indicators
- Ethical Sensory Introvert
- European Stability Initiative
- Export substitution industrialization
- ITT Educational Services
- North Alaskan Inupiatun language