ENTPD6Ectonucleoside triphosphate diphosphohydrolase 6 is an enzyme that in humans is encoded by the ENTPD6 gene.FunctionENTPD6 is similar to E-type nucleotidases. NTPases, such as CD39, mediate catabolism of extracellular nucleotides. ENTPD6 contains 4 apyrase-conserved regions, which is characteristic of NTPases.