EMC
- Dell EMC
- EMC Motorcycles
- EMC Publishing, LLC
- EMC effect
- EMC2 (disambiguation)
- Early Middle Chinese
- Economic Management Council
- Electric membership corporation
- Electro-Motive Corporation
- Electromagnetic compatibility
- Emergency Medical Care
- Encyclopedia of the Medieval Chronicle
- Endoplasmic reticulum membrane protein complex
- Energetically modified cement
- Enhanced Machine Controller
- Entrepreneurial Management Center
- Environmental Modeling Center
- Equilibrium moisture content
- Erode Municipal Corporation
- Essential Media Communications
- European Medical Command
- European Muon Collaboration
- European Music Council
- Evangelical Mennonite Conference
- Evangelical Methodist Church
- Evergreen Marine Corporation
- Extramacrochaetae
- The Xenon Codex