ELOVL4

Elongation of very long chain fatty acids protein 4 is a protein that in humans is encoded by the ELOVL4 gene.
ELOVL4 is a member of a large family of fatty acid elongases that catalyzes the rate-limiting step in the elongation of long chain fatty acids into very long-chain saturated and polyunsaturated fatty acids, collectively known as VLC-FA. ELOVL4 and its products are found in the brain, skin, retina, meibomian glands, testes and sperm. Known mutations of ELOVL4 in humans cause diseases such as Autosomal Dominant Stargardt-like Macular Dystrophy, spinocerebellar ataxia-34, skin deformities and seizures.