Disc
- Absolutely convex set
- Confederation of Revolutionary Trade Unions of Turkey
- Cylinder (disambiguation)
- DISC assessment
- Death-inducing signaling complex
- Defence Intelligence and Security Centre
- Delaware Independent School Conference
- Disc (band)
- Disc (magazine)
- Disc harrow
- Disc number
- Discus (disambiguation)
- Discus throw
- Disk (mathematics)
- Disk storage
- Domestic international sales corporation
- Dundee International Sports Centre
- Everytime You Touch Me
- Floppy disk
- Frisbee
- Galactic disc
- Glossary of plant morphology
- Hard disk drive
- International Symposium on Distributed Computing
- Intervertebral disc
- Optical disc
- Spelling of disc