Dimetofrine
Dimetofrine, also known as dimethophrine or dimetophrine and sold under the brand names Dovida, Pressamina, and Superten, is a medication described as a sympathomimetic, vasoconstrictor, and cardiac stimulant. It is said to be similarly or less effective than midodrine in the treatment of orthostatic hypotension and shows substantially lower potency.
The drug is a selective α1-adrenergic receptor agonist but is also said to have β-adrenergic receptor agonist activity. It is a substituted phenethylamine and is also known as 3,5-dimethoxy-4,β-dihydroxy-N-methylphenethylamine. Its chemical structure is similar to that of desglymidodrine, the active metabolite of midodrine.
Dimetofrine remained marketed only in Italy in 2000.