Dimethylcurcumin
Dimethylcurcumin is a nonsteroidal antiandrogen and a synthetic curcuminoid.
In vitro, it is an androgen receptor inhibitor and shows antiandrogenic activity, although its mechanism of action and effects differ from those of conventional antiandrogens; it is not an antagonist of the AR and instead appears to act as a selective degradation enhancer of certain subpopulations of the AR, for instance those present in the prostate gland.