DelucemineDelucemine is a drug which acts as an NMDA antagonist and a serotonin reuptake inhibitor, and has neuroprotective effects. It was originally investigated for the treatment of stroke and in 2004 was studied as a potential antidepressant.OriginThe structure of delucemine is based on argiotoxin 636, a NMDA antagonist isolated from the venom of Argiope aurantia.