David Wilkie
David Wilkie may refer to:
- David Wilkie (artist), Scottish painter
- David Wilkie (surgeon), British surgeon, scientist and philanthropist
- David Wilkie (footballer), Australian rules footballer
- David Wilkie (swimmer), Scottish swimmer
- David Wilkie (ice hockey), American ice hockey player
- David Wilkie (taxicab driver), Welsh taxi driver killed during the UK miners' strike of 1984–85
- David Lloyd Wilkie or Adam Purple, American activist and guerrilla gardener born as David Lloyd Wilkie