David Roche

• David Roche (footballer), English footballer
• David Roche (Medal of Honor), see List of Medal of Honor recipients for the Indian Wars
• David Roche (runner), American ultramarathon runner, coach, and podcaster
• Sir David Roche, 1st Baronet, Member of the UK Parliament for Limerick City
• David John Roche, United States Navy officer awarded the Navy Cross
• Sir David O'Grady Roche, 5th Baronet