Dapagliflozin/saxagliptin


Dapagliflozin/saxagliptin, sold under the brand name Qtern, is a fixed-dose combination anti-diabetic medication used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes. It is a combination of dapagliflozin and saxagliptin. It is taken by mouth.
The most common side effects include upper respiratory tract infection and, when used with a sulphonylurea, hypoglycaemia.
Dapagliflozin/saxagliptin was approved for medical use in the European Union in July 2016, and in the United States in February 2017.

Medical uses

In the United States, dapagliflozin/saxagliptin is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes.
In the European Union, it is indicated in adults aged 18 years and older with type 2 diabetes:
  • to improve glycemic control when metformin with or without sulphonylurea and either saxagliptin or dapagliflozin does not provide adequate glycemic control.
  • when already being treated with saxagliptin and dapagliflozin.