DSM
- DSM (company)
- DSM-5
- DSM-5-TR
- Deep sea mining
- Deep space maneuver
- Democratic Socialist Movement (Nigeria)
- Democratic Socialist Movement (South Africa)
- Deputy Stage Manager
- Des Moines International Airport
- Design structure matrix
- Deutsche Sammlung von Mikroorganismen und Zellkulturen
- Deutsche Schule Madrid
- Deutsche Schule Montevideo
- Diagnostic and Statistical Manual of Mental Disorders
- Diamond-Star Motors
- Digital surface model
- DiskStation Manager
- Distinguished Service Medal (disambiguation)
- Distributed shared memory
- Doctor (title)
- Doha Securities Market
- Dover Street Market
- Dynamic scattering mode
- Dynamic spectrum management
- Energy demand management
- German School of Milan
- MUMPS
- Team DSM (men's team)