DGKBDiacylglycerol kinase beta is an enzyme that in humans is encoded by the DGKB gene.FunctionDiacylglycerol kinases are regulators of the intracellular concentration of the second messenger diacylglycerol and thus play a key role in cellular processes. Nine mammalian isotypes have been identified, which are encoded by separate genes. Mammalian DGK isozymes contain a conserved catalytic domain and a cysteine-rich domain. The protein encoded by this gene is a diacylglycerol kinase, beta isotype. Two alternatively spliced transcript variants have been found for this gene.