DE
- .de
- Condor (airline)
- DE postcode area
- Daily Express
- De (Chinese)
- De (Cyrillic)
- De (interjection)
- De (kana)
- De (surname)
- De River
- Defence Estates
- Defensive end
- Delaware
- Department of Education
- Desert Eagle
- Design engineer
- Desktop environment
- Destroyer escort
- Dextrose equivalent
- Diatomaceous earth
- Differential equation
- Differential evolution
- Digital Extremes
- Distance education
- Doctor of Engineering
- Douwe Egberts
- Downward entailing
- Dwarf elliptical galaxy
- Dynamics Explorer
- Dé (footballer, born 1940)
- Dé (footballer, born 1998)
- Dé, Mali
- German language
- Germany
- Haplogroup DE (Y-DNA)
- John Deere
- ΔE (color space)