DDM
- 2DM (disambiguation)
- DM (disambiguation)
- Dante (networking)
- Data Diffusion Machine
- Deseret Digital Media
- Dharma Drum Mountain
- Didymoteicho
- Difference in the Depth of Modulation
- Differential dynamic microscopy
- Direct Digital Manufacturing
- Disorders of diminished motivation
- Distributed Data Management Architecture
- Dividend Discount Model
- Doctor of Dental Medicine
- Domain decomposition methods
- Dungeon Dice Monsters
- Dynamic Device Mapping
- East German mark
- German Steam Locomotive Museum
- Maltosides
- Small Form-factor Pluggable
- Top drive