DDC
- DDC-I
- DOPA decarboxylase
- Dairy Development Corporation
- Dansk Datamatik Center
- Deep Dickollective
- Defense Technical Information Center
- Detroit Diesel Corporation
- Dewey Decimal Classification
- Dideoxycytidine
- Digital distribution copy
- Digital down converter
- Direct digital control
- Display Data Channel
- District Development Committee
- District Development Council
- Dodge City Regional Airport
- Double Dealing Character
- Double disc court
- Dzongkha Development Commission
- Open Compute Project
- United States District Court for the District of Columbia