DCS
- Bureau of Diplomatic Security
- Child protective services
- Dade Christian School
- Damage control surgery
- Danish Council of State
- Dark current spectroscopy
- Data Coding Scheme
- Dayton City School
- Deacon (Church of Scotland)
- Dead Celebrity Status
- Deaf Children's Society
- Dean Close School
- Decompression sickness
- Defense Clandestine Service
- Delusional companion syndrome
- Dendritic cells
- Department of Corrective Services
- Departure control system
- Deputy Chief of the Air Staff (disambiguation)
- Deputy Chief of the Defence Staff
- Desert Christian Schools (Arizona)
- Desert Christian Schools (California)
- Desi Culture Shock
- Desktop Color Separations
- Detective Chief Superintendent
- Device Control String
- Dichlorosilane
- Diffuse correlation spectrometry
- Digital Cellular System
- Digital Combat Simulator
- Digital Command System
- Digital Compression System
- Digital cross connect system
- Digital-Coded Squelch
- Diploma of Collegial Studies
- Directorate of Colonial Surveys
- Distributed control system
- Doctors Charter School of Miami Shores
- Dorsal Column Stimulator
- Dry Combat Submersible
- Dutch Council of State
- Dwight Cavendish
- Georgia Department of Community Supervision
- International Maritime Organization
- Kodak DCS
- Northeast Operating Rules Advisory Committee
- White House Deputy Chief of Staff