Cupriavidus metallidurans
Cupriavidus metallidurans is a non-spore-forming, Gram-negative bacterium which is adapted to survive several forms of heavy metal stress.
As a model and industrial system
Cupriavidus metallidurans is a bacterial species that belongs to the same family as Ralstonia solanacearum, a plant pathogen.This species is of ecological and industrial importance, as its relatives dominate mesophilic environments contaminated with heavy metals. C. metallidurans is used in the industrial sector for both heavy metal remediation and sensing.
This aerobic chemolithoautotroph is capable of growing in a mineral salts environment with H2, O2, and CO2 without an organic carbon source. Its energy-providing subsystem is composed of only the hydrogenase, the respiratory chain, and the F1F0-ATPase, which remain separate from the anabolic subsystems.
C. metallidurans can also degrade xenobiotics in conditions with high levels of heavy metals.
Strain CH34 has adapted to these harsh conditions through multiple heavy-metal resistance systems, encoded by the two indigenous megaplasmids, pMOL28 and pMOL30, on its chromosome.