Conserved Function of lincRNAs in Vertebrate Embryonic Development despite Rapid Sequence Evolution
Conserved Function of lincRNAs in Vertebrate Embryonic Development despite Rapid Sequence Evolution is a scholarly work by David P. Bartel and Igor Ulitsky, published in 2011 in ''Cell''. The main subjects of the publication include RNA sequencing, long non-coding RNA, genetics, biological sequence, evolutionary biology, conserved sequence, Vertebrata, biological function, biology, microRNA, RNA splicing, computational biology, and embryonic stem cell. The study provides a roadmap for identification and analysis of lincRNAs in model organisms and shows that lincRNAs play crucial biological roles during embryonic development with functionality conserved despite limited sequence conservation.