Completely randomized design

In the design of experiments, completely randomized designs are for studying the effects of one primary factor without the need to take other nuisance variables into account. This article describes completely randomized designs that have one primary factor. The experiment compares the values of a response variable based on the different levels of that primary factor. For completely randomized designs, the levels of the primary factor are randomly assigned to the experimental units.

Randomization

To randomize is to determine the run sequence of the experimental units randomly. For example, if there are 3 levels of the primary factor with each level to be run 2 times, then there are 6! possible run sequences. Because of the replication, the number of unique orderings is 90. An example of an unrandomized design would be to always run 2 replications for the first level, then 2 for the second level, and finally 2 for the third level. To randomize the runs, one way would be to put 6 slips of paper in a box with 2 having level 1, 2 having level 2, and 2 having level 3. Before each run, one of the slips would be drawn blindly from the box and the level selected would be used for the next run of the experiment.
In practice, the randomization is typically performed by a computer program. However, the randomization can also be generated from random number tables or by some physical mechanism.

Three key numbers

All completely randomized designs with one primary factor are defined by 3 numbers:k = number of factors L = number of levelsn = number of replications
and the total sample size is N = k × L × n. Balance dictates that the number of replications be the same at each level of the factor.

Example

A typical example of a completely randomized design is the following:k = 1 factor L = 4 levels of that single factor n = 3 replications per levelN = 4 levels × 3 replications per level = 12 runs

Sample randomized sequence of trials

The randomized sequence of trials might look like: X₁: 3, 1, 4, 2, 2, 1, 3, 4, 1, 2, 4, 3
Note that in this example there are 12!/ = 369,600 ways to run the experiment, all equally likely to be picked by a randomization procedure.

Model for a completely randomized design

The model for the response is
withY_i,j being any observation for which X₁ = i

μ is the general location parameterT_i is the effect of having treatment level ''i''

Estimates and statistical tests

Estimating and testing model factor levels

Estimate for μ : = the average of all the data
Estimate for T_i :

with = average of all Y for which X₁ = i.
Statistical tests for levels of X₁ are those used for a one-way ANOVA and are detailed in the article on analysis of variance.