SH 265runs, starting at a junction with I-70 in Denver. The highway then turns northeast and runs along Brighton Boulevard, entering Commerce City. It then goes over Sand Creek and passes under I-270 without any access to it. The road continues northeast and ends at a junction with US 6 / US85 in northern Commerce City. Most of its segment inside Denver is maintained locally.
History
The current alignment of SH 265 was originally a part of US 85 before it was rerouted onto Vasquez Boulevard in 1942, with SH 265 being designated over it. The section south of York Street was part of the original routing of SH 224 until 1954, when it was rerouted and SH 265 was extended south onto this segment where it existstoday.