Codon-Substitution Models for Detecting Molecular Adaptation at Individual Sites Along Specific Lineages
Codon-Substitution Models for Detecting Molecular Adaptation at Individual Sites Along Specific Lineages is a scholarly work, published in 2002 in ''Molecular Biology and Evolution''. The main subjects of the publication include evolutionary dynamics, Directional selection, Synonymous substitution, evolutionary biology, substitution, ribosome, biology, gene, Nonsynonymous substitution, codon usage bias, natural selection, purifying selection, genetics, neutral mutation, phylogenetics, RNA sequencing, ocular adaptation, molecular evolution, and selection (genetic algorithm). The authors apply those branch-site models as well as previous branch- and site-specific models to three data sets: the lysozyme genes from primates, the tumor suppressor BRCA1 genes from primates, and the phytochrome (PHY) gene family in angiosperms.