Clamp loader ATPases and the evolution of DNA replication machinery


Clamp loader ATPases and the evolution of DNA replication machinery is a scholarly work by John Kuriyan and Michael O'Donnell, published in 2012 in ''BMC Biology''. The main subjects of the publication include DNA polymerase processivity factor complex, biology, deoxyribonucleic acid, epigenetics, DNA replication, cell biology, DNA repair, Processivity, DNA polymerase, biophysics, DNA polymerase delta, clamp, loader, molecular evolution, and ATPase. The authors review here the current understanding of the clamp loader mechanism and discuss the implications of the differences between clamp loaders from the different branches of life.

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