Chromodoris dianae can reach a maximum size of 4 cm length. The body is elongate with a foot which is distinct from the upper body by a skirt like mantle partially hiding the foot. This species is very similar in appearance to Chromodoris lochi although it can be distinguished from the latter by the brokenblacklines, and the sprinkling of whitespecks on the notum. Chromodoris dianae has white gills and rhinophores with distinct yellow-orange tips. The original description includes animals which belong to another species which are distinguished by a colour pattern which includes gills and rhinophores orange throughout, orange markings at the edge of the mantle and a different pattern of black markings; confirmed as species level differences by DNA sequences.