| Rank | Name | Image | Height
| Floors | Year | Coordinates | Notes |
| 1 | Bank of America Corporate Center | | 871 | 60 | 1992 | | It is the 456th-tallest building in the world, the 54th-tallest in the United States, the tallest building in North Carolina, the tallest building between Philadelphia and Atlanta, the tallest building constructed in Charlotte in the 1990s, and the tallest office building in the Carolinas. However, with of space it is only the 2nd-largest office building in Charlotte by leasable square feet; the largest is 550 South Tryon. |
| 2 | 550 South Tryon | | 786 | 48 | 2010 | | 550 South Tryon is the 851st-tallest in the world, the 97th-tallest in the United States, and the 2nd-tallest in North Carolina. With of space it is the largest office building in Charlotte by leasable square feet. |
| 3 | Truist Center | | 659 | 47 | 2002 | | Truist Center is the 3rd-tallest in North Carolina. It has of space, which makes it the 5th-largest office building in Charlotte by leasable square feet. |
| 4 | Bank of America Tower | | 632 | 33 | 2019 | | Bank of America Tower is the 4th-tallest in North Carolina. With of space, it is the 8th-largest office building in Charlotte by leasable square feet. |
| 5 | Duke Energy Plaza | | 629 | 40 | 2022 | | It has of space, which makes it the 3rd-largest office building in Charlotte by leasable square feet. |
| 6 | 301 South College | | 588 | 42 | 1988 | | 301 South College is the 6th-tallest in North Carolina. It has of space, which makes it the 4th-largest office building in Charlotte by leasable square feet. |
| 7 | The Vue | | 576 | 50 | 2010 | | The Vue is the 7th-tallest in North Carolina and it is the tallest residential building in the Carolinas. |
| 8 | One South at The Plaza | | 503 | 40 | 1974 | | One South at The Plaza is the 9th-tallest in North Carolina. With of space, it is the 7th-largest office building in Charlotte by leasable square feet. |
| 9 | 1 [Bank of America Center] | | 484 | 32 | 2010 | | 1 Bank of America Center is the 10th-tallest in North Carolina. With of space, it is the 9th-largest office building in Charlotte by leasable square feet. |
| 10 | 300 South Tryon | | 463 | 25 | 2017 | | 11th-tallest in North Carolina. With of space it is the 14th-largest office building in Charlotte by leasable square feet. |
| 11 | 121 West Trade | | 462 | 32 | 1990 | | 12th-tallest in North Carolina. |
| 12 | Three Wells Fargo Center | | 450 | 32 | 2000 | | 14th-tallest in North Carolina. It contains of space, which makes it the 6th-largest office building in Charlotte by leasable square feet. |
| 13 | Museum Tower | | 447 | 42 | 2017 | | 15th-tallest in North Carolina. It has 394 units built on top of the Mint Museum Uptown. It has resort-style amenities on the 43rd floor, with a saltwater pool, a lounge and a game room. |
| 13 | 201 North Tryon | | 447 | 30 | 1997 | | 15th-tallest in North Carolina. The tower was developed by Trammel Crow Co. for Bank of America. It is the 12th-largest office building in Charlotte by leasable square feet. |
| 15 | Two Wells Fargo Center | | 433 | 32 | 1971 | | 18th-tallest in North Carolina. With of space it is the 9th-largest office building in Charlotte by leasable square feet. |
| 16 | Avenue | | 425 | 36 | 2007 | | 19th-tallest in North Carolina. It is a 387-unit condo building on.8 acres developed by Novare Group Inc. |
| 17 | 400 South Tryon | | 420 | 32 | 1974 | | It is the 21th-tallest in North Carolina. In April 2025 the building was put up for public auction. The only bid was for $36 million, from the lender, listed as 400 South Tryon LP. At the time of the auction the building was 23% occupied. |
| 18 | Carillon Tower | | 394 | 24 | 1991 | | 23rd-tallest in North Carolina. It is the 19th-largest office building in Charlotte by leasable square feet. |
| 19 | Charlotte Plaza | | 388 | 27 | 1982 | | 25th-tallest in North Carolina. In November 2024 the building was listed for sale, with 60% occupancy. Also, the building is in special loan negotiations with the lender. |
| 20 | The Ellis | | 384 | 33 | 2021 | | 549 apartment units with of retail. It is one of the tallest residential towers in Charlotte, and the 14th-largest apartment complex in the Charlotte area. |
| 21 | Ally Charlotte Center | | 378 | 26 | 2021 | | Construction started in December 2016 and the building delivered on May 3, 2021. With of space it is the 11th-largest office building in Charlotte by leasable square feet. |
| 22 | FNB Tower Charlotte | | 371 | 29 | 2021 | | Anchored by FNB Corporation, with of office space, 196 luxury apartments, and of retail space. It broke ground in December 2018. The building opened on July 21, 2021. |
| 23 | Lowe's Global Technology Center | | 357 | 23 | 2021 | | It sits across the street from the Design Center of the Carolinas and is anchored by Lowe's. Construction started August 2019. It is the tallest building outside Uptown. |
| 24 | Radius Dilworth Overlook | | 345 | 26 | 2025 | | The complex is composed of 2 apartment towers with a combined total of 626 units with of ground level retail. It is the 7th-largest apartment community in the Charlotte area. It is also the tallest building in Dilworth |
| 24 | Oro Ballantyne | | 345 | 26 | 2025 | | It is a 26-story apartment tower that will have 365 units that is split between the high-rise and mid-rise buildings located in Ballantyne Corporate Park as part of The Bowl, which is a part of the Ballantyne Reimagined project. |
| 26 | Catalyst | | 338 | 27 | 2009 | | With 462 apartments it is the 23rd-largest apartment complex in the Charlotte area. |
| 26 | Ascent Uptown | | 338 | 33 | 2017 | | It contains 300 units, with of amenities on the top 2 floors |
| 28 | Honeywell Tower | | 331 | 23 | 2021 | | The building contains of leasable space, which makes it the 27th-largest office building in Charlotte. |
| 29 | 525 North Tryon | | 330 | 19 | 1999 | | With of space it is the 24th-largest office building in Charlotte by leasable square feet. |
| 30 | TradeMark | | 325 | 28 | 2007 | | |
| 31 | First Citizens Plaza | | 320 | 23 | 1987 | | In April 2023 the property was returned to the lender after the owner defaulted on the loan. At that time the building was 43% occupied. |
| 32 | Kingston South End | | 318 | 24 | 2024 | | It is a 24-story residential tower with 324 apartments and of ground floor retail. |
| 32 | 600 South Tryon | | 318 | 24 | 2025 | | It is the 4th office tower that is a part of the Legacy Union project. The 24-story tower contains, which makes it the 25th largest office building in Charlotte by square footage. |
| 32 | Linea | | 318 | 24 | 2025 | | It is an apartment tower with 370 units along with of ground-floor retail and restaurant space. It is being built next to the completed The Line where Sycamore Brewing relocated. |
| 35 | The Arlington | | 310 | 24 | 2002 | | It was the tallest building outside of Uptown Charlotte until Lowe's Global Technology Center was completed in 2021. |
| 35 | Skye | | 310 | 22 | 2013 | | It is a 172-room Hyatt Place hotel and contains 69 condos with a restaurant on the 20th floor. |
| 37 | 110 East | | 305 | 23 | 2024 | | It is a office tower with of street level retail. This square footage makes it the 28th largest office building in Charlotte and the largest building in South End. |
| 38 | One Independence Center | | 301 | 22 | 1983 | | It contains of space it is the 18th largest office building in Charlotte by leasable square feet. |
| 39 | 200 South College | | 300 | 22 | 1974 | | The building contains it is the 7th largest office building in Charlotte by leasable square feet. |
| 39 | AC Hotel/Residence Inn Charlotte EpiCentre | | 300 | 18 | 1961 | | Tallest building constructed in Charlotte in the 1960s. |
| 42 | The Westin Charlotte | | 293 | 25 | 2003 | | It contains 700 rooms, making it the largest hotel in Charlotte by number of rooms. |
| 42 | 550 South | | 293 | 20 | 2009 | | |
| 44 | The Hilton Charlotte Center City | | 292 | 22 | 1990 | | With 400 rooms it is the 5th largest hotel in Charlotte by number of rooms. |
| 45 | 650 S Tryon | | 291 | 18 | 2020 | | Second office tower planned on the Legacy Union development site. Construction completed mid November 2020. |
| 46 | 112 Tryon Plaza | | 280 | 22 | 1927 | | Tallest building constructed in Charlotte in the 1920s. |
| 46 | JW Marriott Charlotte | | 280 | 22 | 2021 | | Construction started in December 2018. With 381 rooms it is the 7th largest hotel in Charlotte by number of rooms. The hotel opened August 17, 2021. |
| 48 | Bell Uptown Charlotte | | 278 | 22 | 2014 | | 22-story 352-unit apartment tower across the street from Romare Bearden Park, developed by Childress Klein. It was sold to Bell Partners in June 2022 for $165 million. |
| 49 | The Howard R. Levine Center for Education | | 270 | 14 | 2025 | | It will be the Wake Forest University School of Medicine Charlotte campus main education tower containing medical school classrooms. |
| 50 | The Ascher Uptown Apartments North Tower | | 264 | 24 | 2015 | | One of 2 twin residential towers that combined feature 672 apartments, which makes it the 5th largest apartment complex in the Charlotte area. |
| 50 | The Ascher Uptown Apartments South Tower | | 264 | 24 | 2017 | | One of 2 twin residential towers that combined feature 672 apartments, which makes it the 5th largest apartment complex in the Charlotte area. |
| 52 | Regions 615 | | 260 | 19 | 2017 | | It contains of leasable space. Regions Financial anchors the building. The building also contains 300 MUFG Union Bank employees. |
| 53 | Charlotte Marriott City Center | | 252 | 19 | 1984 | | It contains 446 rooms, which makes it the 2nd largest hotel in Charlotte by number of rooms. |
| 53 | Omni Charlotte Hotel | | 252 | 19 | 1977 | | With 373 rooms it is the 8th largest hotel in Charlotte by number of rooms. |
| 55 | 129 West Trade | | 250 | 17 | 1958 | | Tallest building constructed in Charlotte in the 1950s. |
| 56 | Le Méridien Charlotte | | 238 | 18 | 1973 | | The hotel was previously part of the Blake Hotel, which had 605 rooms. In early 2015 the former hotel completed a $20 million renovation to become The Sheraton and Le Méridien. Le Méridien is the 11th largest hotel in Charlotte by number of rooms. |
| 56 | Sonesta Charlotte Executive Park | | 238 | 18 | 1983 | | The hotel is owned by Hospitality Properties Trust, purchased in 2017 for $44 million. With 300 rooms it is the 11th largest hotel in Charlotte by number of rooms. In 2014 a $10 million renovation was finished. |
| 58 | The Francis Apartments | | 230 | 19 | 2018 | | $150 million mixed used development by Crescent Communities and CNM Enterprises in Uptown Charlotte. It contains 459 apartments, a and of additional retail space. |
| 59 | Kimpton Tryon Park | | 226 | 18 | 2017 | | With 217 rooms it is the 25th largest hotel in Charlotte by number of rooms. |
| 59 | Bond on Mint | | 226 | 17 | 2025 | | It is a 17-story apartment building located at the corner of Mint St and Morehead St in South End with 393 units. |
| 61 | Ritz-Carlton Charlotte | | 225 | 17 | 2009 | | 150 room hotel built by Bank of America for $500 million combined cost for 1 Bank of America Center and the hotel. The bank has an agreement with the hotel to cover their losses in order to keep the hotel open. Also, bank employees will receive discounted rates. |
| 61 | Johnston Building | | 225 | 17 | 1924 | | In December 2024 Charlotte City Council approved a redevelopment of the entire building to become a 245-room hotel. |
| 63 | Uptown 550 | | 223 | 21 | 2019 | | 21 story apartment tower that along with a 6-story building contains 421 apartments. |
| 64 | Charlotte-Mecklenburg Government Center | | 214 | 14 | 1988 | | |
| 65 | 440 South Church | | 212 | 16 | 2009 | | The building contains, Ally Financial anchored the building from 2009 to moving into Ally Charlotte Center in 2021. |
| 65 | Towerview at Ballantyne | | 212 | 16 | 2021 | | Announced in October 2019 by Northwood Ravin as Ballantyne Corporate Park's first apartment tower. The 16-story building with an attached low-rise building have 212 apartments. The building was part of the early stages of Ballantyne Reimagined. |
| 65 | The Line | | 212 | 16 | 2022 | | A 16-story building developed by Portman. Foundry Commercial became the first tenant of the building starting on May 16, 2022. |
| 68 | Capitol Towers North | | 200 | 10 | 2017 | | Developed by Charlotte-based Lincoln Harris, located in South Park on a site behind Piedmont Town Center. The towers were built as speculative buildings, with no tenants signed on prior to construction. |
| 68 | Capitol Towers South | | 200 | 10 | 2015 | | Developed by Charlotte-based Lincoln Harris, located in South Park on a site behind Piedmont Town Center. The towers were built as speculative buildings, with no tenants signed on prior to construction. |
| Name | Height
| Floors | Year | Notes |
| ANOVA | 265 | 20 | 2028 | The building is a 20-story apartment building being built at The Pearl with 382 units, with 19 units reserved for low-income residents. In 2021 Atrium promised that affordable housing would be a part of the district. The Construction will begin in the first half of 2026 and deliver in 2028. |
| 900 South McDowell | 238 | 18 | | Northwood Ravin is developing an 18 story 328 unit apartment building at 900 South McDowell, right next to The Pearl. The developer purchased the 1.3 acre property for $11.25 million in June 2025 from Duncan-Parnell. The building should break ground in 2026. |
| Southern Land Company Residential Tower | 397 | 30 | 2026 | It is a mixed-use tower with 300 luxury apartments that will be built on the former site of Tyber Creek Pub. It is being developed by Southern Land Company on a parcel at the corner of Tremont Ave and South Blvd which combines lots 1919, 1923 and 1933 South Blvd. The historic building at 1923 South Blvd., which was part of the land purchased by Southern Land Company, was relocated to 1829 Cleveland Ave. Tyber Creek closed on March 18, 2024. |
| Carson & Tryon Office Building | 411 | 31 | 2025 | It is a 31-story mixed use tower with of office space, 200 room hotel, of retail, and 200 residential units. The site is currently occupied by an Enterprise Rent-A-Car location at the corner of Carson and Tryon at 1102 S Tryon St. The developers Crescent Communities and Nuveen Real Estate paid $37 million for the four parcels from different owners that make up the site. Crescent Communities applied for building permits with Mecklenburg County on October 14, 2024, although a ground breaking date has not been set. Charlotte's largest law firm Moore & Van Allen will anchor the building. The firm currently occupies at Bank of America Corporate Center. It is unclear how much space the firm will occupy in the new building. |
| Carson & Tryon Hotel | 265 | 20 | 2025 | 200 room hotel that is a part of the development Carson & Tryon. The development also includes a 31-story mixed use tower with of office space, of retail, and 200 residential units. The site is currently occupied by an Enterprise Rent-A-Car location at the corner of Carson and Tryon at 1102 S Tryon St. The developers Crescent Communities and Nuveen Real Estate paid $37 million for the four parcels from different owners that make up the site Construction will start in 2023 and complete in 2025. |
| 1728 South Blvd. | 265 | 20 | 2025 | Office Tower that will be a joint venture between White Point Partners, MRP Realty and Barings with of office space, ground floor retail, and a rooftop terrace. The building will be near Ascent South End. It will be built on the lot that Walgreens once occupied and the store will be built on the ground floor once complete. Construction will begin in 2023. |
| VeLa Uptown | 368 | 32 | 2026 | 379 luxury apartments which are being developed at 200 E. Seventh St., former site of the Levine Museum of the New South. The site at the corner of East Seventh and North College was purchased on March 13, 2022, for $10.75 million. It will also include of retail and of resident amenity space. The project cost is $170 million. Construction will begin in 2025 and complete in the 4th quarter of 2026. |
| 205 E Bland St | 265 | 20 | 2026 | Cousins Properties is planning a office building on a parking lot. The building will also include ground-floor retail and onsite parking. The lot was purchased in November 2020 as part of a larger $28.1 million deal that also gave Cousins nearby parking lot 1401 S. Tryon St. and 200 E. Bland St. |
| 2915 Griffith | 265 | 20 | 2026 | building on a lot located directly next to Suffolk Punch and across from Lynx Blue Line's New Bern Station in South End, construction will start in the second quarter of 2022 and finish in 2024. |
| Camden Exchange | 398 | 30 | 2026 | Apartment tower with 315 units, of ground floor retail, and of office space occupied by Catalyst. It is being developed by Catalyst Capital Partners and Stiles Corp and it will be built on the former site of Price's Chicken Coop located at 1600 and 1604 Camden Road. It will break ground in late 2024. |
| Intercontinental Hotel at Belk Place | 451 | 34 | 2026 | It will contain 244 room luxury hotel, which will make it the 22nd largest hotel in Charlotte by number of rooms. Construction started in February 2018, on hold due to the COVID-19 pandemic's effect on the Charlotte hotel business Will become the tallest hotel in the Southern United States outside of Atlanta upon completion. The hotel developer, Salter Brothers, announced in June 2023 the project is back on track. Construction will start in summer 2024 and complete in mid-2026. |
| 1427 South Blvd | 411 | 31 | 2027 | Washington, D.C. developer Akridge and Virginia-based property management company Kettler are developing a 31-story 450 unit apartment building on a lot. The building will also include ground level retail, a resort style pool, fitness center, and co-working space. The companies purchased the lot on December 20, 2022, for $13.5 million. It is currently occupied by businesses Modern Man, Savvy Seconds Consignment, Fresh Nails, Lucky Fish and Destined To Make It. It will break ground in 2024. |
| Brooklyn Village Phase 1 Office Tower 1 | 318 | 24 | 2026 | It is a 24-story office tower that is being built as a part of the Brooklyn village development phase 1. This is 1 of 2 office towers totaling. It will be built upon a 5.75-acre lot that was previously occupied by Bob Walton Plaza at 700 E. Brooklyn Village Ave. The land sold in July 2023 for $10.3 million. In September 2023 the demolition of Bob Walton Plaza began and construction will complete in late 2026. |
| Brooklyn Village Phase 1 Office Tower 2 | 212 | 16 | 2026 | It is a 16-story office tower being built as a part of the Brooklyn village development phase 1. This is the second of 2 office towers totaling. It will be built upon a 5.75-acre lot currently occupied by Bob Walton Plaza at 700 E. Brooklyn Village Ave, which will be made up of 6 parcels. The land sold in July 2023 for $10.3 million. In September 2023 the demolition of Bob Walton Plaza began and construction will complete in late 2026. |
| 401 South College | | | 2027 | Animal investment firm and Millennium Venture Capital in December 2022 purchased the building for $24 million. The site is 2.3 acres. However, Charlotte Regional Visitors authority swapped a 1.9-acre parcel at 501 South Caldwell St for a.7-acre parcel on the site at the corner of College Street and Martin Luther King Jr. Blvd. A 1.6-acre site remains available for the development, which will be divided into two parcels. On one of the parcels will be a high-rise multifamily tower with 350 to 400 units. Construction is expected to start in late 2025. |
| South End Station Building 1 | 212 | 16 | | Cousins Properties is planning a 2 building mixed use complex at 200 E Bland; where All American Pub, Hot Taco and Slate are currently located. The complex will include a potential 300 multifamily units, retail and office space. The lot was purchased in November 2020 as part of a larger $28.1 million deal that also gave Cousins nearby parking lots 1401 S. Tryon St. and 205 E. Bland St. |
| South End Station Building 2 | 212 | 16 | | Cousins Properties is planning a 2 building mixed use complex at 200 E Bland; where All American Pub, Hot Taco and Slate are currently located. The complex will include a potential 300 multifamily units, retail and office space. The lot was purchased in November 2020 as part of a larger $28.1 million deal that also gave Cousins nearby parking lots 1401 S. Tryon St. and 205 E. Bland St. |
| Tremont Alley Office Building | 251 | 19 | | Cousins is building a office tower on West Tremont across from the Common Market. The building will also contain of ground floor retail and the building will sit on podium parking. It will occupy a 2.4-acre lot that was purchased in December 2020 for $18.7 million that was composed of 3 parcels 242 Tremont Ave., 306 Tremont Ave., and 305 Dogget St.. The lot is currently vacant, the previous industrial building have been demolished. |
| Tremont Alley Apartment Building | 251 | 19 | | Cousins is building a 305-unit residential tower on West Tremont across from the Common Market. The building will also contain of ground floor retail and the building will sit on podium parking. It will occupy a 2.4-acre lot that was purchased in December 2020 for $18.7 million that was composed of 3 parcels 242 Tremont Ave., 306 Tremont Ave., and 305 Dogget St. The lot is currently vacant, the previous industrial building has been demolished. |
| 1426 S Tryon St. | 265 | 20 | | Highwoods Properties Inc. in May 2022 purchased the lot across the street from the Railyard for $27 million. Currently occupying the site is a low-rise building containing an ABC store. A mixed-use building with of office space and 250 apartments is planned. |
| 1435 South Tryon | 318 | 24 | | Cousins Properties is planning a 24 story mixed tower on the site of a surface parking lot. It will have office space and a multifamily component. The land was part of a 2.2 acre $20 million purchase in November 2020 that also included 200 East Bland. The development of 1435 South Tryon and 200 East Bland will break ground in a year or two. |
| 1175 Pearl Park Way | 275 | | | Pappas Properties is a planning a three building development in midtown that is the final phase of a multi phase development in the area. The three building includes a 275-foot apartment tower with 425 units, 150-room hotel, of office space, of retail on a 2.2-acre lot. |