Charles Le Moyne

• Charles Le Moyne (actor), American actor of the silent film era
• Charles le Moyne de Longueuil et de Châteauguay, settler in New France, now Canada
• Charles le Moyne de Longueuil, Baron de Longueuil, governor in New France
• Charles Le Moyne Mitchell, American politician
• Charles LeMoyne Hospital, a hospital in Greenfield Park, Quebec, Canada