Charles Caldwell

• Charles Caldwell (bluesman), American blues musician
• Charles Caldwell (physician), American physician, founder University of Louisville School of Medicine
• Charles Caldwell (politician), political leader in Reconstruction-era Mississippi
• Charles Henry Bromedge Caldwell, United States Navy officer during the American Civil War
• C. Pope Caldwell, American politician from the state of New York
• Charlie Caldwell, American baseball pitcher and football coach