Central Railway
- Alabama Central Railroad
- Alaska Central Railroad
- Algoma Central Railway
- American Central Railway
- Anglesey Central Railway
- Argentine Central Railway
- Arizona Central Railroad
- Belfast Central Railway
- Bombay, Baroda and Central India Railway
- Buenos Aires Central Railway
- California Central Railway
- Canada Central Railway
- Cape Breton and Central Nova Scotia Railway
- Central Argentine Railway
- Central Australia Railway
- Central Branch (Long Island Rail Road)
- Central Branch Union Pacific Railroad
- Central California Traction Company
- Central China Railway
- Central Chubut Railway
- Central City Railway
- Central East African Railways
- Central Entre Ríos Railway
- Central Highlands Tourist Railway
- Central Illinois Railroad
- Central Indiana and Western Railroad
- Central Iowa Railway
- Central Japan Railway Company
- Central Kansas Railway
- Central Line (disambiguation)
- Central London Railway
- Central Maine and Quebec Railway
- Central Manitoba Railway
- Central Massachusetts Railroad
- Central Michigan Railway
- Central Midland Railway
- Central Montana Rail, Inc.
- Central New England Railway
- Central New York Railroad
- Central Northern Railway
- Central Ohio Railroad
- Central Ontario Railway
- Central Oregon and Pacific Railroad
- Central Pacific Railroad
- Central Plains Metropolitan Region intercity railway
- Central Railroad of Indiana
- Central Railroad of Indianapolis
- Central Railroad of New Jersey
- Central Railroad of Pennsylvania
- Central Railroad of Pennsylvania (1891–1918)
- Central Railway (India)
- Central Railway (UK)
- Central Railway Building
- Central Railway Metro station
- Central Railway Station (disambiguation)
- Central South African Railways
- Central Swabian Railway
- Central Texas and Colorado River Railway
- Central Trains
- Central Uruguay Railway
- Central Vermont Railway
- Central Wales Extension Railway
- Central Washington Railroad
- Central Western railway line, Queensland
- Central of Georgia Railway
- Central of Tennessee Railway and Navigation Company
- Central railway station (London)
- Chennai Central–Bangalore City line
- Chicago Central and Pacific Railroad
- Colorado Central Railroad
- Columbia River and Oregon Central Railroad
- Córdoba Central Railway
- Delmarva Central Railroad
- Derry Central Railway
- East Fife Central Railway
- Enid Central Railway
- Estrada de Ferro Central do Brasil
- Ferrocarril Central Andino
- Florida Central Railroad (1868–1882)
- Florida Central Railroad (1907–1914)
- Florida Central Railroad (current)
- Florida Central and Peninsular Railroad
- Forest of Dean Central Railway
- Georgia Central Railway
- Glasgow Central Railway
- Grand Central (disambiguation)
- Grand Crimean Central Railway
- Great Central Main Line
- Great Central Railway
- Great Central Railway (Nottingham)
- Great Central Railway (disambiguation)
- Great Central Railway (heritage railway)
- Great Lakes Central Railroad
- Great Western and Great Central Joint Railway
- Houston and Texas Central Railway
- Hull and Barnsley and Great Central Joint Railway
- Huron Central Railway
- Illinois Central Gulf Railroad
- Illinois Central Railroad
- Indiana Central Railway
- Isle of Wight Central Railway
- Jersey Central Traction Company
- Lee County Central Electric Railway
- Maine Central Railroad Company
- Maryland Central Railroad
- Mexican Central Railway
- Michigan Central Railroad
- Mississippi Central Railroad (1852-1874)
- Mississippi Central Railroad (1904-1967)
- Montana Central Railway
- Nebraska Central Railroad
- Nevada Central Railroad
- New England Central Railroad
- New York Central Railroad
- Nipissing Central Railway
- North Central Oklahoma Railway
- North Central Railway College
- Northern Central Railway
- Nuevo Central Argentino
- Ohio Central Railroad (1988)
- Ohio Central Railroad System
- Oklahoma Central Railroad (1914–1942)
- Oklahoma Central Railway (1905-1914)
- Oregon Central Rail Road
- Otago Central Railway
- Ottawa Central Railway
- Philadelphia and Baltimore Central Railroad
- Prairie Central Railway
- Prairie Dog Central Railway
- Quebec Central Railway
- Rockland Central Railroad
- Salsette–Trombay Railway
- Scottish Central Railway
- Sha Tin to Central Link
- South Central Florida Railroad
- Swiss Central Railway
- Tennessee Central Railway
- Texas Central Railway
- Toledo and Ohio Central Railway
- Trans-Caspian Railway
- Utah Central Railroad (1869–1881)
- Utah Central Railway (1992)
- Virginia Central Railroad
- Virginia Central Railway
- Waterloo Central Railway
- West Virginia Central and Pittsburg Railway
- Wisconsin Central Railroad (1871–1899)
- Wisconsin Central Railroad (1954–1961)
- Wisconsin Central Railway (1897–1954)
- Wyoming Central Railway
- Württemberg Central Railway
- Zentralbahn