CefteramCefteram is a third-generation cephalosporin antibiotic.SynthesisThe reaction of 7-aminocephalosporanic acid with the methyl-substituted tetrazole gives the intermediate. Protection with diazodiphenylmethane produces. Amide formation with the thiazole carboxylic acid gives, which is deprotected with trifluoroacetic acid to yield cefteram.