CSE
- CAS/CSE protein family
- Calcutta Stock Exchange
- Canadian Securities Exchange
- Casablanca Stock Exchange
- Center for Sustainable Enterprise
- Centre for Science and Environment
- Certificate of Secondary Education
- Chalmers School of Entrepreneurship
- Child sexual exploitation
- Chittagong Stock Exchange
- Chronic solvent-induced encephalopathy
- Circumstellar envelope
- Citizens for a Sound Economy
- Civil Services Examination
- Clinical sleep educator
- Clube Sociedade Esportiva
- Cochin Stock Exchange
- Cognitive systems engineering
- Collaborative search engine
- College of Saint Elizabeth
- Collège du Saint-Esprit
- Colombo Stock Exchange
- Combined Services Entertainment
- Combined spinal and epidural anaesthesia
- Common subexpression elimination
- Communications Security Establishment
- Comparison shopping engine
- Compañía Sevillana de Electricidad
- Comprehensive sex education
- Computational science and engineering
- Computer science and engineering
- Conference of Socialist Economists
- Control systems engineering
- Copenhagen Stock Exchange
- Corpus Speculorum Etruscorum
- Council of Science Editors
- Creation Science Evangelism
- Cyprus Stock Exchange
- Cystathionine gamma-lyase
- Czech Sign Language
- Order of the Star of Ethiopia
- Supreme Electoral Council (Nicaragua)