CLT
- Canadian Learning Television
- Capitol Land Trust
- Central limit theorem
- Central location test
- Charlotte Douglas International Airport
- Charlotte, North Carolina
- Chile Standard Time
- Chronic lymphocytic thyroiditis
- Cilebut railway station
- Classic Learning Test
- Clinical Laboratory Technologist
- Clot lysis time
- Cognitive load theory
- Communicative language teaching
- Community land trust
- Compagnie Luxembourgeoise de Radiodiffusion
- Consolidation of Labor Laws
- Construal level theory
- Cross-laminated timber
- Culture Commission
- Kozhikode railway station