CLR
- Calcium Lime Rust
- California Law Review
- Central London Railway
- Chief Langalibalele Rifles
- Circle of Liberal Reformers
- Circuit layout record
- Cliff Hatfield Memorial Airport
- Cockpit Resource Management
- Coffee leaf rust
- Commando Logistic Regiment
- Common Language Runtime
- Commonwealth Law Reports
- Compagnie Luxembourgeoise de Radiodiffusion
- Council on Library Resources
- Current-Limiting Resistor
- Introduction to Algorithms
- List of United States Marine Corps regiments
- London Underground
- Mercedes-Benz CLR
- Thomson Reuters
- Transaction log