CLIC6

Chloride intracellular channel protein 6 is a protein that in humans is encoded by the CLIC6 gene.
The CLIC6 gene encodes a member of the chloride [intracellular channel] family of proteins. The gene is part of a large triplicated region found on chromosomes 1, 6, and 21. An alternatively spliced transcript variant has been described, but its biological validity has not been determined.

Interactions

CLIC6 has been shown to interact with Dopamine [receptor D3].

Function

CLIC6 has been shown to form chloride selective redox and pH regulated ion channels. It is predominantly expressed in the plasma membrane of lung epithelial cells.