CHS
- CHS Inc.
- Calumet High School (Calumet, Michigan)
- Camas High School
- Canadian Hemophilia Society
- Canadian Hydrographic Service
- Cannabinoid hyperemesis syndrome
- Canton High School (Massachusetts)
- Castor High School
- Catholic High School, Melaka
- Catholic High School, Petaling Jaya
- Catholic High School, Singapore
- Cedar City High School
- Centennial High School (Howard County, Maryland)
- Center for Healthy Sex
- Center for Hellenic Studies
- Central Health Service
- Cerebral hyperperfusion syndrome
- Chalcone synthase
- Chalmette High School
- Chaparral High School (disambiguation)
- Charles-Haden Savage
- Charleston International Airport
- Charlotte High School (disambiguation)
- Chattahoochee High School
- Chattahoochee High School (Florida)
- Cheadle Hulme School
- Cheshire
- Cheshire High School
- Cienega High School
- Clarence High School (India)
- Clayton High School (Missouri)
- Clements High School
- Cleveland High School (Portland, Oregon)
- Clifton High School (Bristol)
- Clifton High School (New Jersey)
- Colegio Hebreo Sefaradí
- College Historical Society
- Collinsville High School
- Columbine High School
- Community Health Systems
- Conard High School
- Conestoga High School
- Confidential human source
- Congleton High School
- Connecticut Historical Society
- Contact Handling System
- Cootamundra High School
- Core Humanitarian Standard on Quality and Accountability
- Crater High School
- Cronulla High School
- Custer High School (Custer, South Dakota)
- Cylinder-head-sector
- Government of India
- Winston Churchill High School (Potomac, Maryland)