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CDCA5


WP:SE
Sororin is a protein that in humans is encoded by the CDCA5 gene.

Function

Sororin is required for stable binding of cohesin to chromatin and for sister chromatid cohesion in interphase.

Clinical significance

Transactivation of Sororin and its phosphorylation at Ser209 by ERK play an important role in lung cancer proliferation.

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